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GLP-1 titration schedule
Week-by-week escalation schedules from the official semaglutide and tirzepatide labels and the retatrutide phase 2 trial, laid out as a calendar.
| Weeks | Starts | Weekly dose in source |
|---|---|---|
| 1 to 4 | Sep 28, 2026 | 2.5 mg |
| 5 to 8 | Oct 26, 2026 | 5 mg |
| 9 to 12 | Nov 23, 2026 | 7.5 mg |
| 13 to 16 | Dec 21, 2026 | 10 mg |
| 17 to 20 | Jan 18, 2027 | 12.5 mg |
| 21 onward | Feb 15, 2027 | 15 mg |
Once weekly. 2.5 mg is an initiation step. Increases of 2.5 mg happen after at least 4 weeks. Maintenance can stop at 5, 10 or 15 mg. Source: Zepbound US prescribing information.
This lays out a published schedule on a calendar. It is not a prescription. Prescribing GLP-1 medicines belongs with a licensed Philippine physician.