Tirzepatide reconstitution calculator
Tirzepatide reconstitution calculator. Enter vial size and bacteriostatic water to get concentration and the insulin syringe units for any amount.
| Amount | Units (U-100) | mL |
|---|---|---|
| 50 mcg | 0.7 | 0.007 |
| 100 mcg | 1.3 | 0.013 |
| 250 mcg | 3.3 | 0.033 |
| 500 mcg | 6.7 | 0.067 |
| 1 mg | 13.3 | 0.133 |
| 2 mg | 26.7 | 0.267 |
| 2.5 mg | 33.3 | 0.333 |
| 5 mg | 66.7 | 0.667 |
How the math works
Concentration is the peptide in the vial divided by the water you add. A 10 mg vial with 2 mL of bacteriostatic water holds 5 mg (5,000 mcg) per mL. On a U-100 insulin syringe, 1 mL is 100 units, so each unit carries 50 mcg. To draw 250 mcg you would pull 5 units.
The amount field is blank on purpose. This site does not suggest amounts. The Tirzepatide page lists what published studies used.
Doses used in published research
What investigators actually administered, as reported in the cited study. This is a record of the literature, not a recommendation.
| Study | Population | Regimen |
|---|---|---|
| SURMOUNT-1, Jastreboff et al., NEJM 2022 | 2,539 adults with obesity, or overweight plus a weight-related complication, without diabetes | 5, 10 or 15 mg subcutaneous once weekly, 72 weeks including a 20-week dose-escalation period |
| Zepbound US prescribing information (label) | Adults in chronic weight management | Start 2.5 mg weekly for 4 weeks, then 5 mg; increase in 2.5 mg steps after at least 4 weeks; maintenance 5, 10 or 15 mg weekly |
New to this? Read Peptides 101 and the syringe units chart.
Common questions
How much bacteriostatic water should I add to a Tirzepatide vial?
There is no single correct volume. More water makes each unit carry less peptide, which makes small amounts easier to measure; less water keeps volumes small. Most people pick a volume that puts their amount between 5 and 50 units on a U-100 syringe.
What does U-100 mean?
U-100 insulin syringes are marked in units where 100 units equals 1 mL. So 10 units is 0.1 mL regardless of what is in the syringe. Peptide calculators use this scale because insulin syringes are what is widely available in Philippine pharmacies.
Does the calculator work for mg and mcg?
Yes. 1 mg equals 1,000 mcg. Switch the unit next to the amount field and the result updates.
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